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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP5 All Species: 22.73
Human Site: T1217 Identified Species: 50
UniProt: Q13017 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13017 NP_001025226.1 1502 172460 T1217 G I D N P A I T S D Q E L D D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115141 1502 172349 T1217 G I D N P A I T S D Q E L D D
Dog Lupus familis XP_850368 1503 172366 T1218 G I D N P A I T S D Q E L D D
Cat Felis silvestris
Mouse Mus musculus P97393 1501 171908 T1216 G I D N P A I T S D Q E V D D
Rat Rattus norvegicus P81128 1513 172361 E1211 V I P Y E T D E D P R R R N I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512048 1500 171507 T1214 G I D N P A I T S D Q E L D D
Chicken Gallus gallus XP_426439 1505 172078 T1219 G I D N P A I T S D Q E L D D
Frog Xenopus laevis NP_001084674 1477 168747 D1206 S Y E A D V E D P R K R N I L
Zebra Danio Brachydanio rerio XP_001336016 1502 171923 I1216 G G I D N P A I T S D P E Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VX32 1561 178754 A1203 Q Q N A Y Y K A S K K P V A A
Honey Bee Apis mellifera XP_624122 1551 176949 N1204 S G D S I G L N Y N V K E I K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.3 98.3 N.A. 93.6 51.1 N.A. 93.2 91.3 49.2 73.9 N.A. 26.3 29.5 N.A. N.A.
Protein Similarity: 100 N.A. 99.8 99 N.A. 95.1 69.8 N.A. 96.7 95.6 68.3 85.9 N.A. 49 50.4 N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 6.6 N.A. 100 100 0 13.3 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 20 N.A. 100 100 13.3 26.6 N.A. 26.6 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 55 10 10 0 0 0 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 64 10 10 0 10 10 10 55 10 0 0 55 64 % D
% Glu: 0 0 10 0 10 0 10 10 0 0 0 55 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 64 19 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 64 10 0 10 0 55 10 0 0 0 0 0 19 10 % I
% Lys: 0 0 0 0 0 0 10 0 0 10 19 10 0 0 10 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 0 46 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 55 10 0 0 10 0 10 0 0 10 10 0 % N
% Pro: 0 0 10 0 55 10 0 0 10 10 0 19 0 0 0 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 55 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 10 19 10 0 0 % R
% Ser: 19 0 0 10 0 0 0 0 64 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 55 10 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 10 0 0 0 0 10 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 10 10 10 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _